Publications


2019
  • Allenby, Mark C., et al. “Dynamic Human Erythropoiesis in a Three-Dimensional Perfusion Bone Marrow Biomimicry.” Biomaterials, vol. 188, Jan. 2019, pp. 24–37, doi:10.1016/j.biomaterials.2018.08.020.
  • Grilo, Antonio L., and A. Mantalaris. “The Increasingly Human and Profitable Monoclonal Antibody Market.” Trends in Biotechnology, vol. 37, no. 1, Jan. 2019, pp. 9–16, doi:10.1016/j.tibtech.2018.05.014.
  • Grilo, Antonio L., and Athanasios Mantalaris. “Apoptosis: A Mammalian Cell Bioprocessing Perspective.” Biotechnology Advances, Feb. 2019, doi:10.1016/j.biotechadv.2019.02.012.
  • Klontzas, Michail E., et al. “Oxidized Alginate Hydrogels with the GHK Peptide Enhance Cord Blood Mesenchymal Stem Cell Osteogenesis: A Paradigm for Metabolomics-Based Evaluation of Biomaterial Design.” Acta Biomaterialia, Feb. 2019, doi:10.1016/j.actbio.2019.02.017.
  • Tahlawi, Asma, et al. “RGD-Functionalized Polyurethane Scaffolds Promote Umbilical Cord Blood Mesenchymal Stem Cell Expansion and Osteogenic Differentiation.” Journal of Tissue Engineering and Regenerative Medicine, vol. 13, no. 2, Feb. 2019, pp. 232–43, doi:10.1002/term.2784.
  • Messini, Irini, et al. “Assessing the Landscape of Ovarian Serous Borderline Tumors.” International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society, vol. 29, no. 3, Mar. 2019, pp. 572–78, doi:10.1136/ijgc-2018-000086.
2018
  • Novosel, E., et al. “New Approaches to Respiratory Assist: Bioengineering an Ambulatory, Miniaturized  Bioartificial Lung.” ASAIO Journal (American Society for Artificial Internal Organs : 1992), June 2018, doi:10.1097/MAT.0000000000000841.
  • Quiroga-Campano, Ana L., et al. “Energy-Based Culture Medium Design for Biomanufacturing Optimization: A Case Study in Monoclonal Antibody Production by GS-NS0 Cells.” Metabolic Engineering, vol. 47, May 2018, pp. 21–30, doi:10.1016/j.ymben.2018.02.013.
  • Allenby, Mark C., et al. “Ceramic Hollow Fibre Constructs for Continuous Perfusion and Cell Harvest from 3D Hematopoietic Organoids.” Stem Cells International, vol. 2018, 2018, p. 6230214, doi:10.1155/2018/6230214.
  • Tsipa, Argyro, et al. “Optimal Bioprocess Design through a Gene Regulatory Network – Growth Kinetic Hybrid Model: Towards Replacing Monod Kinetics.” Metabolic Engineering, vol. 48, July 2018, pp. 129–37, doi:10.1016/j.ymben.2018.04.023.
  • Misener, Ruth, et al. “Stem Cell Biomanufacturing under Uncertainty: A Case Study in Optimizing Red Blood Cell Production.” AIChE Journal. American Institute of Chemical Engineers, vol. 64, no. 8, Aug. 2018, pp. 3011–22, doi:10.1002/aic.16042.
  • Buldum, Gizem, et al. “Recombinant Biosynthesis of Bacterial Cellulose in Genetically Modified Escherichia Coli.” Bioprocess and Biosystems Engineering, vol. 41, no. 2, Feb. 2018, pp. 265–79, doi:10.1007/s00449-017-1864-1.
2017
  • Allenby, Mark C., et al. “A Quantitative Three-Dimensional Image Analysis Tool for Maximal Acquisition of Spatial Heterogeneity Data.” Tissue Engineering. Part C, Methods, vol. 23, no. 2, Feb. 2017, pp. 108–17, doi:10.1089/ten.TEC.2016.0413.
  • Kang, Yunyi, et al. “Fibronectin Stimulates the Osteogenic Differentiation of Murine Embryonic Stem Cells.” Journal of Tissue Engineering and Regenerative Medicine, vol. 11, no. 7, July 2017, pp. 1929–40, doi:10.1002/term.2090.
  • Tsipa, Argyro, et al. “The Impact of Succinate Trace on PWW0 and Ortho-Cleavage Pathway Transcription in Pseudomonas Putida Mt-2 during Toluene Biodegradation.” Bioresource Technology, vol. 234, June 2017, pp. 397–405, doi:10.1016/j.biortech.2017.03.082.
  • Harrison, Claire N., et al. “Ruxolitinib vs Best Available Therapy for ET Intolerant or Resistant to Hydroxycarbamide.” Blood, vol. 130, no. 17, Oct. 2017, pp. 1889–97, doi:10.1182/blood-2017-05-785790.
  • Vernardis, Spyros I., et al. “Human Embryonic and Induced Pluripotent Stem Cells Maintain Phenotype but Alter Their Metabolism after Exposure to ROCK Inhibitor.” Scientific Reports, vol. 7, Feb. 2017, p. 42138, doi:10.1038/srep42138.
  • Cha, Jae Min, et al. “Mesoderm Lineage 3D Tissue Constructs Are Produced at Large-Scale in a 3D Stem Cell Bioprocess.” Biotechnology Journal, vol. 12, no. 9, Sept. 2017, doi:10.1002/biot.201600748.
  • Pavlakis, Kitty, et al. “Identifiable Risk Factors for Lymph Node Metastases in Grade 1 Endometrial Carcinoma.” International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society, vol. 27, no. 8, Oct. 2017, pp. 1694–700, doi:10.1097/IGC.0000000000001070.
  • Totti, Stella, et al. “Designing a Bio-Inspired Biomimetic in Vitro System for the Optimization of Ex Vivo Studies of Pancreatic Cancer.” Drug Discovery Today, vol. 22, no. 4, Apr. 2017, pp. 690–701, doi:10.1016/j.drudis.2017.01.012.
  • Klontzas, Michail E., et al. “Metabolomics Analysis of the Osteogenic Differentiation of Umbilical Cord Blood Mesenchymal Stem Cells Reveals Differential Sensitivity to Osteogenic Agents.” Stem Cells and Development, vol. 26, no. 10, May 2017, pp. 723–33, doi:10.1089/scd.2016.0315.
  • Papathanasiou, Maria M., et al. “Advanced Model-Based Control Strategies for the Intensification of Upstream and Downstream Processing in MAb Production.” Biotechnology Progress, vol. 33, no. 4, July 2017, pp. 966–88, doi:10.1002/btpr.2483.
2016
  • Reissis, Dimitris, et al. “Current Clinical Evidence for the Use of Mesenchymal Stem Cells in Articular Cartilage Repair.” Expert Opinion on Biological Therapy, vol. 16, no. 4, 2016, pp. 535–57, doi:10.1517/14712598.2016.1145651.
  • Savvopoulos, Symeon, et al. “A Personalized Framework for Dynamic Modeling of Disease Trajectories in Chronic  Lymphocytic Leukemia.” IEEE Transactions on Bio-Medical Engineering, vol. 63, no. 11, Nov. 2016, pp. 2396–404, doi:10.1109/TBME.2016.2533658.
  • Severn, Charlotte E., et al. “Polyurethane Scaffolds Seeded with CD34(+) Cells Maintain Early Stem Cells Whilst Also Facilitating Prolonged Egress of Haematopoietic Progenitors.” Scientific Reports, vol. 6, Aug. 2016, p. 32149, doi:10.1038/srep32149.
  • Chaudhry, Mohammed S., et al. “Missense Mutations in the Perforin (PRF1) Gene as a Cause of Hereditary Cancer Predisposition.” Oncoimmunology, vol. 5, no. 7, July 2016, p. e1179415, doi:10.1080/2162402X.2016.1179415.
  • Klontzas, Michail E., et al. “Investigational Drugs for Fracture Healing: Preclinical & Clinical Data.” Expert Opinion on Investigational Drugs, vol. 25, no. 5, 2016, pp. 585–96, doi:10.1517/13543784.2016.1161757.
  • Tsipa, Argyro, et al. “Transcriptional Kinetics of the Cross-Talk between the Ortho-Cleavage and TOL Pathways of Toluene Biodegradation in Pseudomonas Putida Mt-2.” Journal of Biotechnology, vol. 228, June 2016, pp. 112–23, doi:10.1016/j.jbiotec.2016.03.053.
  • Fauzi, Iliana, et al. “In Vitro Differentiation of Embryonic Stem Cells into Hematopoietic Lineage: Towards Erythroid Progenitor’s Production.” Methods in Molecular Biology (Clifton, N.J.), vol. 1341, 2016, pp. 217–34, doi:10.1007/7651_2015_218.
2015
  • Burnett, A. K., et al. “A Randomised Comparison of the Novel Nucleoside Analogue Sapacitabine with Low-Dose Cytarabine in Older Patients with Acute Myeloid Leukaemia.” Leukemia, vol. 29, no. 6, June 2015, pp. 1312–19, doi:10.1038/leu.2015.38.
  • Velliou, Eirini G., et al. “Towards Unravelling the Kinetics of an Acute Myeloid Leukaemia Model System under Oxidative and Starvation Stress: A Comparison between Two- and Three-Dimensional Cultures.” Bioprocess and Biosystems Engineering, vol. 38, no. 8, Aug. 2015, pp. 1589–600, doi:10.1007/s00449-015-1401-z.
  • Kiparissides, A., et al. “On the Model-Based Optimization of Secreting Mammalian Cell (GS-NS0) Cultures.” Biotechnology and Bioengineering, vol. 112, no. 3, Mar. 2015, pp. 536–48, doi:10.1002/bit.25457.
  • Klontzas, Michail E., et al. “Bone and Cartilage Regeneration with the Use of Umbilical Cord Mesenchymal Stem Cells.” Expert Opinion on Biological Therapy, vol. 15, no. 11, 2015, pp. 1541–52, doi:10.1517/14712598.2015.1068755.